Synonyms
Complement C3,
C3
C3 (β1C/β1A Globulin)
C3 Complement
Special Instructions
Expected Turnaround Time
1 – 2 days
Specimen Requirements
Specimen
1 – 2 days
Volume
1 mL (adult), 0.5 mL (pediatric)
Minimum Volume
Red-top tube, gel-barrier tube, or green-top (heparin) tube.
Container
Remove serum or plasma within 45 minutes and transfer to a plastic transport tube.
Collection
Storage Instructions
Refrigerate
Causes for Rejection
Excessive lipemia (>1500 mg/dL) significantly increases the apparent C3 concentration.
Test Details
Use
Quantitation of C3 is used to detect individuals with inborn deficiency of this factor or those with immunologic disease in whom complement is consumed at an increased rate. These include lupus erythematosus, chronic active hepatitis, certain chronic infections, poststreptococcal and membranoproliferative glomerulonephritis, and others.