Synonyms
Anti-CCP
Anti-citrullinated protein antibodies (ACPA)
Anti-Cyclic Citrullinated Peptide Ab
Cyclic Citrullinated Peptide Antibody
Special Instructions
Expected Turnaround Time
2 – 3 days
Specimen Requirements
Specimen
2 – 3 days
Volume
1 mL
Minimum Volume
0.3 mL (Note: This volume does not allow for repeat testing.)
Container
Red-top tube or gel-barrier tube
Collection
Following collection, serum should be separated from the clot.
Storage Instructions
Room temperature
Causes for Rejection
Hemolysis; lipemia; gross bacterial contamination; addition of azide or other preservative; heat inactivation
Test Details
Use
The presence of CCP antibodies, when considered in conjunction with other laboratory and clinical findings, is an aid in the diagnosis of rheumatoid arthritis (RA). Approximately 70% of RA patients are positive for anti-CCP IgG, while only 2% of random blood donors and control subjects are positive.