This test can be used to follow treatment response in patients being treated for syphilis infection. This assay should not be used to screen for syphilis infection. To screen for syphilis infection, a reflex cascade that includes both RPR and a treponema-specfic assay should be utilized, such as Treponema pallidum (Syphilis) Screening Cascade (082345) or Rapid Plasma Reagin (RPR) Test With Reflex to Quantitative RPR and Confirmatory Treponema pallidum Antibodies (012005). See Related Information to view these tests.